With the aging of China's society, the improvement of people's health awareness and the change of disease spectrum, industry demand continues to rise. It is estimated that in 2019, the industrial added value growth rate of the pharmaceutical manufacturing industry will reach 8%; the main business income will increase by about 15% year-on-year, reaching about 278.3 billion yuan. The pharmaceutical manufacturing industry is showing a rapid development trend, which is also a major development opportunity for the pharmaceutical equipment industry closely related to pharmaceutical production. Today, I mainly talk about the significance of the dryer in the pharmaceutical production process and the market development.
Drying is one of the important aspects in the pharmaceutical production process. In order to improve the quality of pharmaceuticals and meet the needs of pharmaceutical production, it is especially important to improve the technology and quality of the drying equipment. According to the skilled person, the drying technique is to use heat energy to remove moisture (or solvent) from the material, and to take away the vaporized moisture (or solvent) by using a gas stream or a vacuum to obtain a process operation technique for the dried article. “Drying is an indispensable basic operation in the pharmaceutical industry. Different dosage forms, equipment, environments and methods of operation often have large differences in drying conditions.â€
It is understood that the drying of medicines, biological products and other materials is required to be carried out at low temperatures, and some require strict sealing to prevent the external environment from polluting or preventing it from spreading to the outside. Therefore, it requires drying equipment during the drying process. Energy saving, easy operation and so on. In recent years, with the continuous advancement and development of technology, the drying equipment industry has also made great progress. For heat sensitive applications, systems requiring closed or combined drying devices have been developed in recent years for vacuum rotary drying and drum dryers, vacuum vibration dryers, heat pump dryers, and low temperature and low humidity dryers.
Taking the hot air circulation drying box as an example, in recent years, after many upgrades, the hot air circulation drying box has reached the advanced level at home and abroad. It is reported that the CT series hot air circulation oven is the first generation product, the average thermal efficiency is about 30%, and the centrifugal fan is used, the box is externally circulated, and the temperature is controlled by hand. After many transformations, the CT-C series hot air circulation oven has been formed. All the series use axial flow fan, equipped with automatic constant temperature control system, and equipped with computer control system. The thermal efficiency is about 70%. The CT-C series hot air circulation oven uses steam or electricity as the heat source. The axial flow fan heats the air in the way of convective heat transfer of the heat exchanger. The hot air laminar flow passes through the baking tray and the material for heat transfer. Fresh air is replenished from the air inlet, and waste hot air is discharged from the moisture exhaust port, continuously replenishing fresh air and continuously discharging hot and humid air, so as to maintain proper relative humidity in the oven.
Drying is a fundamental part of the pharmaceutical manufacturing process, but it is important for pharmaceutical quality. It is even more urgent to improve the technical level of drying equipment. Taking the microwave drying process of traditional Chinese medicine pellets as an example, from the water content before the current pills are dried, most of them are between 20% and 40%, such as water pills, water honey pills, and concentrated pills. The amount of water is between 4% and 9% (about 12%). How to solve this problem, the industry said that microwave drying is very suitable for this water content.
According to the relevant technical personnel, microwave drying is converted from electrical energy into thermal energy. Microwave energy is directly absorbed by moisture. The moisture inside and inside the material is heated while receiving microwaves. It does not need to be preheated like heat conduction heating. At the same time, the direction of heat conduction is consistent with the direction of wet molecular conduction, which greatly increases the drying rate of the material. Since the heat in the heating is directly derived from the inside of the dried product, the microwave heating device itself does not consume heat, and the thermal efficiency can reach 80% or more. According to the actual test, in the tunnel microwave equipment, only 1.43 kW·h of electricity is consumed for every 1 kg of water evaporated. These factors allow the microwave-dried pill to fully meet the moisture requirements after drying. In addition, due to microwave heating and drying, it is heated and dried from the inside of the material, and has automatic balance performance. Its volumetric thermal effect will result in uniform heating, avoiding large temperature gradients in conventional heating systems. This has a greater significance for materials that are prone to surface hardening during conventional heat drying.
With the rapid development of the pharmaceutical industry, the drying equipment industry will also usher in tremendous development opportunities. However, the opportunities and challenges are coexisting. In order to obtain better development, the drying equipment industry needs to thoroughly study the drying mechanism and material drying characteristics, and develop and improve the dryer under the operating conditions of different materials. Large-scale, high-strength, high-economic, and improved adaptability to raw materials and product quality are the basic trends in the development of dryers. With the emphasis on environmental protection by humans, improving the environmental protection measures of dryers to reduce the leakage of dust and exhaust gas will also be the direction for further research.
Drying is one of the important aspects in the pharmaceutical production process. In order to improve the quality of pharmaceuticals and meet the needs of pharmaceutical production, it is especially important to improve the technology and quality of the drying equipment. According to the skilled person, the drying technique is to use heat energy to remove moisture (or solvent) from the material, and to take away the vaporized moisture (or solvent) by using a gas stream or a vacuum to obtain a process operation technique for the dried article. “Drying is an indispensable basic operation in the pharmaceutical industry. Different dosage forms, equipment, environments and methods of operation often have large differences in drying conditions.â€
It is understood that the drying of medicines, biological products and other materials is required to be carried out at low temperatures, and some require strict sealing to prevent the external environment from polluting or preventing it from spreading to the outside. Therefore, it requires drying equipment during the drying process. Energy saving, easy operation and so on. In recent years, with the continuous advancement and development of technology, the drying equipment industry has also made great progress. For heat sensitive applications, systems requiring closed or combined drying devices have been developed in recent years for vacuum rotary drying and drum dryers, vacuum vibration dryers, heat pump dryers, and low temperature and low humidity dryers.
Taking the hot air circulation drying box as an example, in recent years, after many upgrades, the hot air circulation drying box has reached the advanced level at home and abroad. It is reported that the CT series hot air circulation oven is the first generation product, the average thermal efficiency is about 30%, and the centrifugal fan is used, the box is externally circulated, and the temperature is controlled by hand. After many transformations, the CT-C series hot air circulation oven has been formed. All the series use axial flow fan, equipped with automatic constant temperature control system, and equipped with computer control system. The thermal efficiency is about 70%. The CT-C series hot air circulation oven uses steam or electricity as the heat source. The axial flow fan heats the air in the way of convective heat transfer of the heat exchanger. The hot air laminar flow passes through the baking tray and the material for heat transfer. Fresh air is replenished from the air inlet, and waste hot air is discharged from the moisture exhaust port, continuously replenishing fresh air and continuously discharging hot and humid air, so as to maintain proper relative humidity in the oven.
Drying is a fundamental part of the pharmaceutical manufacturing process, but it is important for pharmaceutical quality. It is even more urgent to improve the technical level of drying equipment. Taking the microwave drying process of traditional Chinese medicine pellets as an example, from the water content before the current pills are dried, most of them are between 20% and 40%, such as water pills, water honey pills, and concentrated pills. The amount of water is between 4% and 9% (about 12%). How to solve this problem, the industry said that microwave drying is very suitable for this water content.
According to the relevant technical personnel, microwave drying is converted from electrical energy into thermal energy. Microwave energy is directly absorbed by moisture. The moisture inside and inside the material is heated while receiving microwaves. It does not need to be preheated like heat conduction heating. At the same time, the direction of heat conduction is consistent with the direction of wet molecular conduction, which greatly increases the drying rate of the material. Since the heat in the heating is directly derived from the inside of the dried product, the microwave heating device itself does not consume heat, and the thermal efficiency can reach 80% or more. According to the actual test, in the tunnel microwave equipment, only 1.43 kW·h of electricity is consumed for every 1 kg of water evaporated. These factors allow the microwave-dried pill to fully meet the moisture requirements after drying. In addition, due to microwave heating and drying, it is heated and dried from the inside of the material, and has automatic balance performance. Its volumetric thermal effect will result in uniform heating, avoiding large temperature gradients in conventional heating systems. This has a greater significance for materials that are prone to surface hardening during conventional heat drying.
With the rapid development of the pharmaceutical industry, the drying equipment industry will also usher in tremendous development opportunities. However, the opportunities and challenges are coexisting. In order to obtain better development, the drying equipment industry needs to thoroughly study the drying mechanism and material drying characteristics, and develop and improve the dryer under the operating conditions of different materials. Large-scale, high-strength, high-economic, and improved adaptability to raw materials and product quality are the basic trends in the development of dryers. With the emphasis on environmental protection by humans, improving the environmental protection measures of dryers to reduce the leakage of dust and exhaust gas will also be the direction for further research.
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